The Department of Medicine has come a long way since its inception as an undifferentiated clinical department in 1986, with its original seven full-time faculty members. Today, the department is the largest department in terms of number of faculty. The department has nine specialties in which faculty with diverse experience is serving the patients, educating students, training residents and conducting high quality research. The Department of Medicine is recognised for the scope and quality of the clinical services it provides, its research activities and excellent scholarly productivity and by the size and success of its undergraduate and postgraduate programmes for teaching and training medical students, residents and fellows. The Department of Medicine was the first clinical department at AKU to expand its residency training programme to four years, as mandated by the College of Physicians and Surgeons, Pakistan.